HLA-DM - Wikipedia, the free encyclopedia HLA-DM (human leukocyte antigen DM) is an intracellular protein involved in peptide presentation by MHC class II. It is encoded by the genes HLA-DMA and ...
CLIP (protein) - Wikipedia, the free encyclopedia In presence of antigen peptide fragments, HLA-DM then binds to the MHC II molecule, releasing CLIP and allowing peptides to bind. MHC II with bound antigen ...
MHC class II - Wikipedia, the free encyclopedia An MHC class II-like structure, HLA-DM, facilitates CLIP removal and allows the binding of peptides with higher affinities. The stable class II MHC is then ...
Russ McCracken: HLA-DM HLA-DM. Introduction. The ability of the immune system to recognize and defend against the introduction of foreign antigens is partially dependent upon the ...
HLA-DM induces CLIP dissociation from MHC class II alpha ... 1995年7月14日 - Human leukocyte antigen DM (HLA-DM) molecules are structurally related to classical MHC class II molecules and reside in the lysosome-like ...
Editing of the HLA-DR-peptide repertoire by HLA-DM. This process is facilitated by the non-classical MHC class II molecule HLA-DM (DM) which catalyzes the removal of CLIP. Up to now it has been unclear whether ...
HLA-DM and HLA-DO, key regulators of MHC-II processing ... 2013年12月8日 - Peptide loading of class II MHC molecules in endosomal compartments is regulated by HLA-DM. HLA-DO modulates HLA-DM function, with ...
Short peptide sequences mimic HLA-DM functions - Johns ... Short peptide sequences mimic HLA-DM functions. Chih-Ling Choub,1, Saied Mirshahidia,2, Katherine Wailen Sua, AeRyon Kimc, Kedar Narayanc,. Stanislav ...
HLA-DM induces clip dissociation from MHC class II αβ ... Abstract. Human leukocyte antigen DM (HLA-DM) molecules are structurally related to classical MHC class II molecules and reside in the lysosome-like ...
